Tackling the Antimicrobial Resistance Crisis
Overuse and misuse of antibiotic agents have contributed to the spread of resistant bacteria, posing a serious health risk that the World Health Organization (WHO) describes as a global health emergency. TAXIS is focused on developing new classes of antibiotic agents to treat life-threatening, multidrug-resistant bacterial infections.
ANTIBIOTIC RESISTANCE: FACTS & FIGURES
At least 2 million people in the United States acquire serious, antibiotic resistant infections every year
Centers for Disease Control, Antibiotic Resistance Threats in the United States, 2013. http://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf. Accessed August 5, 2015.
ANTIBIOTIC RESISTANCE: FACTS & FIGURES
At least 23,000 people die each year in the United States as a result of antibiotic-resistant infections
Centers for Disease Control, Antibiotic Resistance Threats in the United States, 2013. http://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf. Accessed August 5, 2015.
ANTIBIOTIC RESISTANCE: FACTS & FIGURES
Up to 50% of all antibiotics prescribed are not needed or not optimally effective as prescribed
Centers for Disease Control, Antibiotic Resistance Threats in the United States, 2013. http://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf. Accessed August 5, 2015.
ANTIBIOTIC RESISTANCE: FACTS & FIGURES
The average cost of treating a methicillin-resistant Staphylococcus aureus or MRSA infection exceeds ~$35,000 per case
The Journal of Healthcare Contracting, Looking for MRSA. http://www.journalofhealthcarecontracting.com/article-marapr2008-lookingformrsa.asp. Accessed August 5, 2015
ANTIBIOTIC RESISTANCE: FACTS & FIGURES
1 in 10 hospitalized patients in the United States will acquire an infection reflecting an economic burden of $6.7B
Plowman RP, Graves N, Roberts JA. Hospital acquired infection. London Office of Health Economics; 1997
ANTIBIOTIC RESISTANCE: FACTS & FIGURES
No major new types of antibiotics have been developed in the last 30 years
World Health Organization, Antimicrobial Resistance: Global Report on Surveillance 2014. http://www.who.int/drugresistance/documents/surveillancereport/en/. Accessed August 5, 2015
ANTIBIOTIC RESISTANCE: FACTS & FIGURES
MRSA represents 5% of the total cases of antibiotic resistance each year, but accounts for nearly half of the mortalities
Centers for Disease Control and Prevention. Active Bacterial Core Surveillance http://www.cdc.gov/ncidod/dbmd/abcs/meth-case.htm. Accessed August 20, 2015
Mission Statement
Our mission is to discover and develop unique therapeutic agents to address the global health crisis of antimicrobial resistance.